The Nuclear Pore Complex: Oily Spaghetti or Gummy Bear?
نویسنده
چکیده
In this issue, Frey and Görlich (2007) provide new insight into the selective barrier that controls protein traffic through the nuclear pore complex. They show that a single protein domain of the nuclear pore protein Nsp1 can form a hydrogel that allows highly selective access of nuclear transport receptors and their cargos, but rejects other proteins of similar size.
منابع مشابه
Nuclear pore complex glycoproteins contain cytoplasmically disposed O- linked N-acetylglucosamine
A novel form of protein-saccharide linkage consisting of single N-acetylglucosamine (GlcNAc) residues attached in O-linkages directly to the polypeptide backbone has been described (Holt, G. D., and G. W. Hart, 1986, J. Biol. Chem., 261:8049-8057). This modification was found on proteins distributed throughout the cell, although proteins bearing O-linked GlcNAc moieties were particularly abunda...
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متن کاملThe mRNA export in Caenorhabditis elegans is mediated by Ce-NXF-1, an ortholog of human TAP/NXF and Saccharomyces cerevisiae Mex67p.
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ورودعنوان ژورنال:
- Cell
دوره 130 شماره
صفحات -
تاریخ انتشار 2007